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Description
Uehara et al., 1995)

The strong reliance of cancer cells on metabolic pathways that supply acetyl-CoA, has recently raised interest in the potential use of antineoplastic agents targeting acetyl-CoA

(TIF) Abbreviations anti-PD-1: anti-programmed death-1 anti-PD-L1: anti-programmed death ligand-1 AIH: autoimmune hepatitis ALP: alkaline phosphatase ALT: alanine transaminase CYP: cytochrome P450 DI-AIH: drug-induced autoimmune hepatitis DILI: drug-induced liver injury ICI: immune checkpoint inhibitors INR: international normalized ratio irAE: immune-related adverse event NAPQI: N-acetyl-p-benzoquinone imine RCT: randomized clinical trials RUCAM: Roussel Uclaf causality assessment method Declarations Acknowledgement We would like to sincerely thank Kyoko Yoneda (Yokohama City University) for her assistance in preparing the figure

, & Mahatma, O
