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Immunostaining for alpha-SNAP in WT tissue revealed a distribution that largely mirrored the N-cadherin pattern, appearing prominently at the cell periphery and enriched at cell-cell boundary regions

Handling and Safety Research materials may present hazards that are not fully characterized

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With respect to antifolates, several drugs inhibiting key enzymes in folate metabolisms, e.g., dihydrofolate reductase (DHFR), thymidylate synthase (TS), and glycinamide ribonucleotide formyltransferase (GARTFase) [87], were evaluated for FR-targeting and anti-arthritic activity in vitro or in arthritic animals