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[Abstract]2021 Jan 1;11(5):2318-2333

Phase 3 trials provide the large-scale data needed to demonstrate the drug works as claimed

Therefore, modulation of this signaling axis represents a potential therapeutic target for overcoming resistance in cancers refractory to conventional treatments, particularly in the context of ferroptosis

Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome
