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L., Broder, M

Tesofensine works by inhibiting the reuptake of dopamine, norepinephrine, and serotonin, leading to appetite suppression and increased satiety

doi: 10.1016/0304-3940(94)90933-4 16 BarakatW.SafwetN.El-MaraghyN

So it's worth asking if their intake of B12 could be an influence