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Thiocyclam-induced reproductive toxicity, oxidative stress and genomic DNA damage in testicular tissues of rats: protective effects of green tea extract

Activation of this pathway increases the cells ability to neutralize ROS before they can damage proteins, lipids, or DNA

Hepatocyte premature senescence is initiated by oxidative stress, along with reduction of IGF-1 during CCl 4 -induced liver fibrogenesis The area density of Masson staining and SA--gal staining showed that with time, CCl 4 initiated hepatic steatosis on Day 6 and the early stage of fibrosis on Day 28
