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Various factors, such as chronic hyperglycaemia, mitochondrial dysfunction, inflammation, and altered signalling pathways, interact and influence ROS generation and antioxidant capacity in a dynamic and interdependent manner
3.1 Roles of ROS and NO in the pathophysiology of human diseases 3.1.1 Oxidative stress, ROS, inflammatory markers and different types of cancer: Connecting the dots 3.1.1.1 Role in carcinogenesis The mechanism of carcinogenesis is divided into different stages: progression, promotion, and initiation

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