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Autophagy Protects Human Brain Microvascular Endothelial Cells against Methylglyoxal-Induced Injuries, Reproducible in a Cerebral Ischemic Model in Diabetic Rats

Research studies have shown that anthocyanins can neutralize ROS in cells, inhibit the generation of oxidative stress in nerve cells and simultaneously reduce the level of intracellular oxidative stress by effectively activating the production of endogenous antioxidant enzymes 176

indicated that black raspberries (BRBs) could reduce DNMT1 and DNMT3b mRNA levels, thereby demethylating Sfrp4, inhibiting WNT signaling and suppressing esophageal tumorigenesis in rats, a model akin to human ESCC

Survival in patients with COPD is negatively associated with skeletal muscle dysfunction and lower mass, and COPD exacerbations rapidly induce loss of muscle mass and function [178,179,180,181]