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The MMACHC encoded protein dealkylates both adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl) and also decyanates cyanocobalamin (CN-Cbl)

While regular physical activity confers neuroprotection through multiple pathways [109], emerging evidence indicates that sedentary behavior independently contributes to PD risk, possibly via chronic systemic inflammation and reduced cerebral perfusion [110, 111, 112, 113]

Regular use may also support cellular energy metabolism*
