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Description
Dark hyperpigmentation softens significantly, rough skin textures smoothen out, and the skin looks well-rested and uniformly bright
However, given the vital role of mitochondrial dysfunction in pulmonary hypertension pathogenesis [205], [206], reducing mitochondrial oxidative damage may be the mechanism of action of LA
111 Bone disease Bone remodeling is involved in determining bone mass
In summary, autophagy mechanisms in PD involve multi-level autophagic flux disruption, lysosomal failure, mitophagy defects, and inflammatory cross-talk
