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Description
In a separate study, Pirola et al

The cycling approach alternates treatment periods with break periods, typically following patterns like 3-4 months on followed by 1-2 months off, 6 months on followed by 2-3 months off, or flexible cycling based on skin condition assessment and benefit plateau timing

Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects

The proven clinical benefits for skin health come from topical application
