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71 TorresN
To identify the specific mechanisms by which cystine affects bacterial cells, we measured the GSH/GSSG ratios, intracellular ferrous iron concentrations, and ROS levels in bacteria cultured with exogenous cystine
Irreversible inhibitors of GCL, buthionine sulfoxide (BSO) and Cysteine sulfonimide, reduce GSH formation and further inhibit GPX4 activity, promoting ferroptosis alone or enhancing sensitivity to ferroptosis (Yang et al., 2014)
Ping F, Shang J, Zhou J, Song J, Zhang L
