glutathione peroxidase selenium deficiency Mechanism of (GPx) redox pathway. Selenol (-SeH) Glutathione peroxidase (GPx) redox cycle.
Description
Vitamin B12 is an essential nutrient that supports red blood cell formation, DNA synthesis, and neurological function

Glutathione is often called the "master antioxidant" because it is found in nearly every cell in the human body

inactive mutant forms of CDO (e.g., His86Ala, leading to loss of the His that serves as a metal ligand in the active site) did not form any cross-link, and mutant forms of CDO with low activity (e.g., Arg60Ala, which has a markedly decreased affinity for Cys, probably due to the loss of the hydrogen bonding partner for the carboxylate of the substrate) formed the cross-link more slowly

doi: 10.1248/bpb.34.1291
