comparison methylation protocol with and without glutathione Frontiers Methyl Group Metabolism in Differentiation,
Description
Perticone F, Ceravolo R, Pujia A, Ventura G, Iacopino S, Scozzafava A, Ferraro A, Chello M, Mastroroberto P, Verdecchia P, Schillaci G
THP-1derived CAR-shSIRP-M exhibit high levels of CD80, CD86, and TNF- under resting conditions, with significant upregulation of M1-associated and glycolysis-related genes, suggesting CAR modification may bolster M1 polarization via enhanced glycolysis (116)
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While these studies provide valuable scientific insights, they do not establish that the same findings occur in humans
