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Koppula, P., Zhang, Y., Zhuang, L

The main risk factors of HRS include portal hypertension, sepsis caused by spontaneous peritonitis, and cardiac insufficiency is also a high risk factor for HRS (Lenz et al., 2014)

On the other hand, cellular GPx activity level showed a positive correlation with quasi-threshold doses (Dq) and extrapolation numbers but not with general radiosensitivity

In addition, mitochondrial dysfunction in stromal cells is the key causal factor triggering fibrosis-induced ovarian decline, and metformins reversal of ovarian fibrosis converges on related mitochondrial metabolic pathways that are upstream of oxidative stress and inflammation (Umehara et al., 2022)