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3 Results 3.1 L-carnitine supplementation prevented lenvatinib-induced reduction in L-carnitine content and protein expression in the skeletal muscle of rats To investigate whether L-carnitine supplementation prevents lenvatinib-induced reduction in protein expression in the skeletal muscle in vivo , we administered lenvatinib with or without L-carnitine once daily for 14 days to rats

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Monoamine oxidases degrade neurotransmitters and are essential for normal brain metabolism, but an age-related increase in their activity can deplete catecholamine neurotransmitters (dopamine, norepinephrine, and adrenaline), which impairs mental function [144,145]