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2.1.5 IL-22 Several studies have shown that the expression of the Th22 cell cytokine IL-22 is elevated in pruritic PN lesions, which is potentially associated with impaired epidermal proliferation and differentiation and skin inflammation (27, 51)

The added lipotropic agents assist the liver in processing fat cells more efficiently, promoting enhanced fat metabolism and healthier weight management

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In this stage, TSH levels may be slightly elevated on blood tests (3-10 mU/L), and the levels of free T3 and free T4 are going to be normal