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These cells transform to facilitate axonal growth, expressing various proteins, including PMP-22, Krox-20, P-0, and Connexin-32, and promoting the expression of c-Jun and neurotrophic agents like NGF

Early impairment of NGF/TrkA signaling in AD can lead to reduced synaptic vesicle secretion and decreased presynaptic protein expression, resulting in presynaptic functional impairment of cholinergic primary neurons [88]

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