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E.et al (2024)

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Selective MT(2) melatonin receptor antagonist blocks melatonin-induced antinociception in rats

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A comparison with energy restriction

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They further refined the in vivo and in vitro experiments and found that andrographolide enhanced nuclear translocation of Nrf2 and increased the expression of antioxidant genes, alleviating APAP-induced liver oxidative stress damage in mice and reducing HSC activation (Yan et al., 2018b)

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