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E.et al (2024)
Selective MT(2) melatonin receptor antagonist blocks melatonin-induced antinociception in rats

A comparison with energy restriction

They further refined the in vivo and in vitro experiments and found that andrographolide enhanced nuclear translocation of Nrf2 and increased the expression of antioxidant genes, alleviating APAP-induced liver oxidative stress damage in mice and reducing HSC activation (Yan et al., 2018b)
