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Other metals which are present in the environment as industrial pollutants are not able to generate free radicals by shuttling between contiguous oxidation states but it is known that organisms exposed either in their natural environment or in toxicological experiments show signs of oxidative stress, and some metals, such as As, Cd and Hg, are also carcinogenic to humans

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Appl Microbiol Biotechnol (in press) Liu CH, Hwang C, Liao CC (1999) Medium optimization for glutathione production by Saccharomyces cerevisiae