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In our recent study of normal zebrafish, dietary l-carnitine supplementation also increased hepatic carnitine concentration, mitochondrial activity and the mRNA expression of CPT1 ( Reference Li, Li and Qin 27 ) , which was associated with lower body lipid content

In the present study, we used young adult mice to investigate epigenetic responses, because, by this age, PA markers 26 stabilise at an elevated level, and epigenetic changes are expected, but without the confounding effects of oxidative damage that emerge in later life 27

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