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Important factors potentiating AKI in these patients are extracellular volume depletion due to vomiting, diarrhoea, urinary tract obstruction, fluid and electrolyte disturbances, exposure to contrast media, nephrotoxic antibiotics, non-steroidal anti-inflammatory drugs and nephrotoxicity of some of the anti-cancer treatments [24]

Tirzepatide offers similar benefits through a dual-action mechanism (Mounjaro, Zepbound)

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 173(11), 1360

Notably, CTC clusters are emerging as critical mediators of metastasis
