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Inhibition of Candida albicans in vivo and in vitro by antimicrobial peptides chromogranin A-N12 through microRNA-155/suppressor of cytokine signaling 1 axis

P., Schleimer, R

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In line, the antihyperglycemic drug metformin which activates AMP-activated protein kinase (AMPK) but blocks mTOR signaling (and thereby glycolysis) and which also inhibits the OXPHOS cycle by interfering with the electron transport chain interfered with both -glucan- and oxLDL-induced trained immunity of monocytes (Keating et al., 2020)