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Vitamin B12 deficiency as a manifestation of pernicious anemia may occur as part of an autoimmune polyglandular syndrome, frequently in association with type 1 diabetes mellitus, Hashimoto thyroiditis or hypothyroidism, and vitiligo (34

(e) cross-sectional studies with no time restriction, (f) only studies published in English were included due to resource limitations and to ensure accuracy in data extraction and risk-of-bias assessment

For longer-term laboratory storage, freezing at approximately 20C is commonly referenced in research settings to help maintain compound integrity

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