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In addition, LA also inhibits ferroptosis and attenuates fluoride-induced liver injury by modulating the Xc-GSH-GPX4 axis and chelating iron (Cho et al., 2022)

In a 2011 study authors measured DSB in human lymphocytes after a CT angiography and found a significant increase in DSBs 30 min after the scan was complete [58]

Mechanistically, total intracellular iron alone is not the whole storyhow a tumor uses iron (for DNA repair, energy metabolism, redox buffering, etc.) and the cells lineage-specific biology determine whether ferritin acts mainly as a protective iron reservoir or as a regulator of metabolism and redox state [3, 88]