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Most studies use fixed doses, though you'll occasionally see weight-based protocols (110 mcg/kg, or roughly 0.54.5 mcg/lb) in the literature

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2006, Buie T, Campbell DB, Fuchs GJ, Furuta GT, Levy J, Vandewater J, Whitaker AH, Atkins D, Bauman ML, Beaudet AL, Carr EG, Gershon MD, Hyman SL, Jirapinyo P, Jyonouchi H, Kooros K, Kushak R, Levitt P, Levy SE, Lewis JD, Murray KF, Natowicz MR, Sabra A, Wershil BK, Weston SC, Zeltzer L, Winter H: Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report
