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The microbiome is implicated in most inflammatory diseases, including arthritis

Adverse reactions following intramuscular (IM) injection have included anxiety, mild transient diarrhea, ataxia, nervousness, pruritus, transitory exanthema, and a feeling of swelling of the entire body

As these patients were most likely classified as moderate progressors, the results suggested that 50 mg methylcobalamin injections could be beneficial for patients with ALS in the early stage and with moderate progression rate, the researchers wrote

The increase in the production of glutathione and other detoxification enzymes may result in the liberation of these from the body resulting in symptoms