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Description
Amylin acts on (1) appetitive/energy-regulating neurons in the hypothalamus impacting food intake, (2) dopaminergic neurons in the ventral tegmental area impacting reward and motivation, and (3) chemoreceptive neurons in the area postrema/nucleus tractus solitarius [60]
The expression levels of PG0031457 increased was the treatment time increased
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Injectable forms provide faster onset (1530 minutes vs 6090 minutes oral), higher peak plasma concentrations, and more consistent dosing precision
