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Allison DJ, Ditor DS

For instance, hypomethylation of the multidrug resistance 1 (MDR1) gene, which codes for the P-glycoprotein drug efflux pump, can enhance its expression, reducing intracellular drug concentrations and leading to drug resistance [98,2]

This potential synergistic effect is particularly useful in studies that aim to understand the complex interactions of growth hormone secretagogues and their effects on various physiological parameters