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Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single centre, phase 2 pilot trial

Other experimental models of inflammation employing mice are the demonstration of the anti-inflammatory potential of sulforaphane in lung diseases using cigarette smoke-induced alveolar damage [66], cigarette smoke-exposed asthmatic mice [170], bleomycin-induced pulmonary fibrosis [171], ovalbumin (OVA)-sensitised and cigarette smoke-induced airway inflammation [172], chlorine-induced airway hyper-responsiveness [173], haemorrhagic shock-induced lung injury [174], OVA-induced chronic allergic airways [175], lipopolysaccharide (LPS)-induced acute lung injury [176], respiratory syncytial virus (RSV)-induced bronchopulmonary inflammation [177], and the pulmonary arterial hypertension model [178]

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In functional medicine it may be used as supportive care for gastritis, ulcer recovery, and leaky gut, with the protocol tailored to the patient by the provider