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Emerging treatment modalities like immunotherapy, gene therapy, and personalized medicine more recently offer promising avenues but also present a big challenge in terms of cost, accessibility, and resistance development [22,26,27,28]
The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators
doi: 10.1016/j.cgh.2010.01.007 273 TariqRPardiDSBartlettMGKhannaS
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