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[PMC free article] [PubMed] [Google Scholar] 40.Yamaoka K., Vogel S.M., Seyama I

Although an excessive increase was observed in Tumour necrosis factor (TNF-), interleukin-1 (IL-1), and interleukin-6 (IL-6), as well as mitochondrial oxidative stress, apoptosis and TRPV1 channel overactivations in DRG and SN neurons under OX treatment, Se suppressed these negative effects

PTMs play a key role in various biological processes by affecting the structure, reactivity, stability, and function of the protein, thereby modulating a broad range of biological processes (3)