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Yun et al
This use has been supported by a double-blind clinical trial showing that, once alcohol use is stopped, milk thistle can reverse some of alcohol-induced liver damage
Their resistance has been linked to their capacity to reduce ROS levels through the accumulation of intracellular antioxidants like glutathione and the induction of GCL, as demonstrated in breast and liver TICs [18,19,20]
DREADDs with different coupling properties can be expressed in a cell type-specific fashion, for example by generating transgenic mice or by using virus-based delivery techniques
