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This study revealed that NPI-001 (NACA), NPI-002 (diNACA) and NAC exhibited varying degrees of antioxidant activity, i.e., protected cultured rat retinal cells from a variety of stressors which were designed to mimic aspects of the pathology of different retinal diseases

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[ 1 ] Heterodimers of BACH1MAF bind to MAF recognition elements (MAREs, a unique DNA sequence of 5TGACTCGCA3) in the target gene promoters, thereby suppressing or initiating genes transcription

Of note, MAO-A appears to be the predominant isoform expressed in the hiPSCs, whereas MAO-B is absent and appears only after 40 days of differentiation, in mature hiPSC-CMs [19]