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Moreover, the total GSH levels of the organism decrease by age [28] and by disease, as diabetes mellitus [247] and HIV infection [248]

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GSH is the most important hydrophilic antioxidant that protects cells against exogenous and endogenous toxins, including reactive oxygen (ROS) and nitrogen (RNS) species (Rauhala et al., 2005

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Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells

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