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Epithelialmesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

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Notwithstanding, identifying genes that are repositories and/or transducers of epigenetic parental inheritance it is of pivotal interest to develop epigenetic screening able to promptly identify newborns susceptible to developing dysmetabolism in adulthood, alert them of their increased risks, and suggest preventive lifestyles, and, eventually, pharmacological treatments

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