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Cells were incubated with BODIPY 493/503 (10 M) for 1 h at 37C, washed once with HBSS, and resuspended in RPMI 1640 (Gibco)
Given that osimertinib is the recommended first-line medication for patients with EGFR-mutated NSCLC according to international guidelines (Schiefer et al., 2018
Beyond the frequently altered and therapeutically targeted receptor tyrosine kinase (RTK) pathways in HCC, pathways involved in cell differentiation, telomere regulation, epigenetic modification and stress response also provide therapeutic potential
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