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In addition, and importantly, the simultaneous consumption of caffeine and taurine included in EDs may have multiple effects on the cardiovascular system, different from the effects expected when these compounds are used separately

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Rao RD, Flynn PJ, Sloan JA, et al

Birth Defects, Decreased IQ, and Neurodevelopmental Disorders Inform pregnant women and women of childbearing potential (including girls beginning the onset of puberty) that use of valproate during pregnancy increases the risk of birth defects, decreased IQ, and neurodevelopmental disorders in children who were exposed in utero [see Warnings and Precautions (5.2, 5.3, 5.4) and Use in Specific Populations (8.1)]