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Endogenous control limits: The pituitary cannot be pushed beyond its capacity

doi: 10.1371/journal.pone.0071272 60 CampagnaRSalvoliniEPompeiVPozziVSalvucciAMolinelliEet al

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Oxidative stress, compressive overload, nutrient stress, enhanced inflammation, and other factors can act on these parts and stimulate aberrant cellular responses and progressive structural deficiency, leading to disc degeneration 32
