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However, a protective effect on the host can be induced when the timing of C

In addition, in a multicenter study of buprenorphine taper schedules, after 3 weeks of flexible dosing of buprenorphine, participants with longer past heroin use or those who injected opioids were more likely to receive higher dose buprenorphine by the final week [31]

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The indirect costs of IC/BPS, including time away from work and lost productivity while working, are particularly significant since the condition primarily affects working age adults, and especially women aged 25-50 years