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These findings are consistent with earlier reports describing an inverted U-shaped doseresponse relationship, underscoring the importance of further investigation into the pharmacodynamic profile of GlyT1 inhibitors

doi: 10.3184/095422914X14047407349335 289 RigobeloE

Statins were initially known as lipid-lowering and cholesterol-lowering drugs

and Bertin, G., 2008
