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Studies analyzing cytokines and chemokines in the plasma of patients with Wilson disease have enhanced our understanding of the underlying mechanisms and confirmed that the disease is driven by dysregulated inflammatory mediators [61,64,67]

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Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor recognized as a major regulator of oxidative stress and metabolic homeostasis (Dodson et al., 2019

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