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10.1186/s13065-024-01139-w BMC Chem

Approximately 75% of carnitine in the human body is derived from dietary sources, such as animal products such as red meat and dairy products (with high amine content), and 25% is synthesized endogenously from lysine and methionine in the liver and kidneys

Some researchers suggest that bacterial DNA may activate macrophages and trigger the innate immune system via TLR2 and TLR4, which influence plaque stability (Mitra et al

To date, there is only one approved medication available to treat ALS, namely riluzole, which only increases survival by 3 months (Bensimon et al., Energy metabolism disturbances in ALS There are many lines of evidence for the role of disturbed energy metabolism in ALS pathogenesis