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Experimental applications include investigation of receptor-specific signaling bias, ligandreceptor affinity profiles, and downstream transcriptional responses mediated by melanocortin receptor subtypes

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Zhong, L., Feng, Y., Wang, G., Wang, Z., Bilal, M., Lv, H., Cui, J

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At the same time, the plasma CYP3A4 content increased in the research group immediately and 12 months after CE, indicating that 4OH-CHO is also one of the biological activity markers of CYP3A4 and suggesting the regulation of 4OH-CHO-CYP3A4 as the future direction for further research

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Primary Research Areas Melanocortin receptor signaling: non-selective MC1/MC3/MC4/MC5 agonist used to map downstream melanocortin pathways in CNS and peripheral tissues

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