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Product Specifications Compound: AOD-9604 Class: Synthetic peptide fragment / growth hormone C-terminal analog Origin: C-terminal fragment of human growth hormone (residues 177-191) with N-terminal tyrosine addition Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Molecular Weight: ~1815 Da Form: Lyophilized powder Vial Size: 5mg in 3mL glass vial Purity: 99%+ verified by HPLC and mass spectrometry (See COAs) Research Context AOD-9604 is utilized in research applications involving peptide chemistry , growth hormone fragment research , and cellular research applications

Penile erection mainly depends on the activation of NO/cGMP signal pathway and the function of PDE5 is to block the decomposition of cyclic guanosine monophosphate (cGMP) ( PDE5Is are the first-line treatment for erectile dysfunction ( In addition to acting on PDE5 of cavernous smooth muscle, PDE5I also inhibits PDE5 and its isozymes in blood vessels, viscera, skeletal muscle, platelets, and other tissues, causing reactions in multiple systems

10.1161/ATVBAHA.109.193375 Arterioscler Thromb Vasc Biol