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Furthermore, excitotoxic damage has been shown to significantly elevate HO-1 protein expression in primary astrocyte cultures, accompanied by translocation of the protein to the nucleus (Li et al., 2004)

The pathophysiology of hypertension involves a complex interaction of multiple vascular effectors including the activation of the sympathetic nervous system, of the reninangiotensinaldosterone system and of the inflammatory mediators

Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease