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Additionally, tolerability was evaluated immediately pre-dose, at the time of administration (injection-site reactions [ISRs] only), 5 minutes, and 2, 4, 6, 12 and 24 hours after each injection

doi: 10.1016/j.mad.2015.12.001

Stimulant actions in rodents: implications for attention-deficit/hyperactivity disorder treatment and potential substance abuse
Sonawane and Pokharkar reported the development of quercetin-loaded NLCs (QT-NLC) integrated into an intranasal in situ gel to enhance cerebral delivery and therapeutic efficacy against neurodegeneration in rats