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B vitamins generally have a low risk of interacting with medications, though some supplements can cause interference
The immune-fighting cells have already been primed, so the theoretical conceptwhich we know happens with many other already FDA-approved vaccines like tetanus or whooping coughis that the booster doses increase immunity over time
[1] Removal of the colon by surgery may be necessary if the disease is severe, does not respond to treatment, or if complications such as colon cancer develop
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