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For instance, a randomized phase II study utilized dynamic hypoxia imaging ([ 18 F]FMISO PET/CT) to guide and escalate radiation dose specifically to hypoxic subvolumes in head and neck cancer, demonstrating the feasibility and prognostic value of such image-guided, radical-focused dose painting (NCT02352792) [159]

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Many investigations show that Al 3+ can elicit impairment of development and immunity
