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It is inactivated when combined with Fe3+(SR780@Fe) and is released and activated only under weakly acidic conditions, realizing the precise treatment of cancer cells

Given the toxicity of cordycepin to host cells, improving cell tolerance to cordycepin stress and elucidating its underlying mechanisms are crucial for constructing efficient cell factories

726 Conversely, reducing these proteins can synergistically enhance the effectiveness of ionizing radiation and anti-PD-L1 therapies in reducing cancer burdens

Curcumin is often described as a hormetic compound because it induces an adaptive stress response: it mildly stresses cells in ways that activate Nrf2 and other transcription factors, leading to increased production of antioxidant and cytoprotective proteins (e.g., heme oxygenase-1) that precondition cells against subsequent injuries (77, 78)