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Description
The sheer mechanical demands placed on this joint make it vulnerable to multiple types of damage

Thus, it is possible that the senescent phenotype drives the accumulation of CD38 + inflammatory cells, which modulate the availability of NAD + precursors, and plays a crucial role in the metabolism of nicotinamide nucleotide (Figure 5) (65)

Separate needles should be used for reconstitution and administration

*J Orthop Res.* 28(9):1155-1161
